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Jeffrey B Kopp Selected Research

Apolipoprotein L1

1/2022Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice.
1/2022Impact of APOL1 kidney risk variants on glomerular transcriptomes.
1/2022APOL1 Risk Variants Associated with Serum Albumin in a Population-Based Cohort Study.
10/2021The key role of NLRP3 and STING in APOL1-associated podocytopathy.
1/2021APOL1 genotype-associated morphologic changes among patients with focal segmental glomerulosclerosis.
1/2019APOL1 renal risk variants promote cholesterol accumulation in tissues and cultured macrophages from APOL1 transgenic mice.
11/2018APOL1-Associated Nephropathy: A Key Contributor to Racial Disparities in CKD.
1/2018Fetal-Not Maternal-APOL1 Genotype Associated with Risk for Preeclampsia in Those with African Ancestry.
1/2018ApoL1 renal risk variants induce aberrant THP-1 monocyte differentiation and increase eicosanoid production via enhanced expression of cyclooxygenase-2.
3/2016A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.
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Jeffrey B Kopp Research Topics

Disease

35Kidney Diseases (Kidney Disease)
01/2022 - 09/2002
31Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
02/2022 - 02/2006
27Proteinuria
01/2022 - 06/2005
22Fibrosis (Cirrhosis)
01/2022 - 03/2002
16Chronic Kidney Failure (Chronic Renal Failure)
01/2022 - 08/2003
15Chronic Renal Insufficiency
04/2022 - 09/2007
15Diabetic Nephropathies (Diabetic Nephropathy)
01/2022 - 02/2010
13Albuminuria
10/2021 - 06/2005
12Hypertension (High Blood Pressure)
01/2022 - 04/2009
11Inflammation (Inflammations)
01/2022 - 01/2002
11Infections
01/2021 - 02/2003
9AIDS-Associated Nephropathy (HIV-Associated Nephropathy)
10/2019 - 08/2003
8Wilms Tumor (Wilm's Tumor)
10/2020 - 02/2007
7Glomerulonephritis
01/2021 - 04/2002
6Acute Kidney Injury (Acute Renal Failure)
01/2022 - 09/2004
6HIV Infections (HIV Infection)
01/2019 - 08/2003
5Lupus Nephritis
01/2022 - 01/2010
5Nephrotic Syndrome (Syndrome, Nephrotic)
01/2019 - 02/2006
4Membranous Glomerulonephritis (Membranous Nephropathy)
01/2022 - 03/2010
4Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 01/2018
4Obesity
01/2021 - 12/2013
4Insulin Resistance
12/2013 - 02/2008
3IGA Glomerulonephritis (IGA Nephropathy)
01/2022 - 06/2009
3Neoplasms (Cancer)
01/2022 - 11/2004
3Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2022 - 04/2002
3Autoimmune Diseases (Autoimmune Disease)
01/2022 - 04/2002
3Interstitial Nephritis (Tubulointerstitial Nephritis)
01/2021 - 04/2002
3Disease Progression
10/2019 - 03/2002
3Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
01/2018 - 04/2015
2Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 01/2018
2Virus Diseases (Viral Diseases)
01/2022 - 01/2005
2Nephritis
12/2021 - 08/2010
2Sickle Cell Trait
01/2018 - 07/2017
2Type 2 Diabetes Mellitus (MODY)
01/2018 - 11/2009
2Stroke (Strokes)
01/2018 - 07/2017
2Thrombotic Microangiopathies
03/2015 - 03/2008
2Hyperglycemia
12/2014 - 11/2010
2Lipodystrophy
09/2013 - 02/2008
2Cicatrix (Scar)
02/2011 - 01/2003

Drug/Important Bio-Agent (IBA)

26Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2003
19Apolipoprotein L1IBA
01/2022 - 09/2010
10Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2008
9Messenger RNA (mRNA)IBA
01/2021 - 06/2009
8CreatinineIBA
01/2022 - 01/2011
7Transforming Growth Factor beta1 (TGF beta 1)IBA
01/2022 - 04/2004
7CytokinesIBA
12/2019 - 01/2002
6AlbuminsIBA
01/2022 - 06/2005
5RNA (Ribonucleic Acid)IBA
02/2022 - 10/2017
5LipidsIBA
01/2022 - 12/2014
5NPHS2 proteinIBA
10/2020 - 02/2006
5AutoantibodiesIBA
12/2019 - 04/2002
5nephrinIBA
12/2014 - 02/2007
5Myosin Heavy Chains (Myosin Heavy Chain)IBA
01/2013 - 01/2009
4Glucose (Dextrose)FDA LinkGeneric
07/2022 - 04/2004
4InterferonsIBA
01/2022 - 02/2015
4MicroRNAs (MicroRNA)IBA
01/2022 - 04/2015
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 03/2008
4CholesterolIBA
01/2021 - 07/2014
4EnzymesIBA
01/2019 - 09/2004
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018 - 11/2010
4Pharmaceutical PreparationsIBA
01/2016 - 09/2004
3InflammasomesIBA
01/2022 - 01/2018
3Protein Kinases (Protein Kinase)IBA
01/2022 - 01/2013
3ErythropoietinFDA Link
01/2021 - 07/2007
3Folic Acid (Vitamin M)FDA LinkGeneric
01/2021 - 12/2011
3SteroidsIBA
11/2018 - 11/2007
3Streptozocin (Streptozotocin)FDA Link
01/2018 - 11/2010
3vpr Gene ProductsIBA
10/2017 - 02/2008
3Transforming Growth Factors (Transforming Growth Factor)IBA
08/2015 - 03/2010
3podocalyxinIBA
04/2012 - 03/2010
3pirfenidoneIBA
06/2011 - 09/2007
2Circular RNAIBA
01/2022 - 10/2020
2ApolipoproteinsIBA
01/2021 - 10/2016
2Triglycerides (Triacylglycerol)IBA
01/2021 - 02/2007
2InterleukinsIBA
01/2021 - 12/2011
2CollagenIBA
01/2021 - 10/2020
2Fibronectins (Fibronectin)IBA
01/2021 - 04/2004
2ChemokinesIBA
01/2021 - 10/2020
2Doxorubicin (Adriamycin)FDA LinkGeneric
12/2020 - 03/2010
2Serum AlbuminIBA
08/2020 - 02/2006
2Monoclonal AntibodiesIBA
12/2019 - 03/2008
2DNA (Deoxyribonucleic Acid)IBA
12/2019 - 11/2004
2AngiotensinsIBA
01/2019 - 02/2007
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2019 - 06/2015
2Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
01/2018 - 12/2011
2Urokinase Plasminogen Activator ReceptorsIBA
01/2018 - 08/2017
26alpha-ethyl-23(S)-methylcholic acidIBA
01/2018 - 01/2016
2Antihypertensive Agents (Antihypertensives)IBA
10/2017 - 01/2013
2Tenofovir (Viread)FDA Link
01/2016 - 05/2013
2Antigen-Antibody Complex (Immune Complex)IBA
03/2015 - 11/2008
2AntibodiesIBA
03/2014 - 03/2010
2Transforming Growth Factor beta (TGF-beta)IBA
09/2011 - 08/2007
2Tretinoin (Retinoic Acid)FDA LinkGeneric
02/2011 - 01/2010
2Angiotensin IIIBA
12/2010 - 10/2007
2Hydralazine (Apresoline)FDA LinkGeneric
12/2010 - 10/2007

Therapy/Procedure

26Therapeutics
01/2022 - 04/2002
7Kidney Transplantation
10/2019 - 01/2003
4Nephrectomy
01/2022 - 01/2005
2Precision Medicine
01/2018 - 01/2018
2Highly Active Antiretroviral Therapy (HAART)
05/2013 - 08/2003